Suffolk County police say 29-year-old Christopher Marino and 23-year-old girlfriend Jamie Greco, both of Medford, began their spree in early December and targeted including fast-food restaurants and gas stations.
They say he stole the cash, while she operated as a getaway driver.
Six of the incidents happened at Subway restaurants and four others at gas stations, but the couple allegedly also robbed a KFC, Carvel, 7-Eleven, Mobil on the Run and Royal Market.
They are charged with 13 counts of first-degree robbery and two counts of first-degree attempted robbery. They are being held on $3 million bond.