Police say 21-year-old Luis Sarmiento was running across the southbound lanes near milemarker 139.7 just before 1 a.m.
He was struck by two vehicles, both of which pulled over on the side of the highway.
Sarmiento, of Riverside, was apparently running across the highway after getting into a previous two-car crash.
He jumped out of his Honda Accord and ran across the parkway into the southbound lanes, where he was struck.
State Police closed the southbound lanes of the Parkway for several hours as they investigated.
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