The suspects were caught on camera during the January 17th incident.
Police say they forced their way into a room at the Harlem Vista Hotel on Macombs Place and robbed its occupants.
The suspects are both described as black males, 5'9" to 5'11", medium build and armed with a silver handgun.
Anyone with information is asked to call Crime Stoppers at (800) 577-TIPS (8477).
Get Eyewitness News Delivered