The Jets announced Wednesday that Holmes, who will require surgery, was placed on season-ending injured reserve. The team signed free agent wide receiver Jason Hill to help replace him.
The news comes just over a week after star cornerback Darrelle Revis was likely lost for the season with a torn ligament in his left knee.
Holmes went down on the first play of the fourth quarter Sunday after catching a short pass. X-rays on the foot were negative, but the MRI exam results were sent to a foot specialist in North Carolina and the Jets' worst fears were confirmed.
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