Police were called to 1457 East 102nd Street in Canarsie at 2:27 p.m. on a report of a woman assaulted.
There, they found 18-year-old Lakeshia Seymour unconscious inside the home, bleeding from her head. She was pronounced dead at the scene.
A Good Samaritan tried to help the driver after the crash, and police say the suspect pulled a knife on him. That man was uninjured.
The suspect ran into a nearby cemetery, where police eventually arrested him.
Charges against Simon are pending.