The men were taken into custody during a round up of suspects wanted in an ongoing gunpoint robbery spree.
They were being questioned by detectives investigating the killing of 23-year-old Rabie Muhammed.
Muhammed was walking with her husband Sunday night when they were accosted by a group of men, who demanded her purse.
She refused to turn it over, and was fatally shot.
Her husband was not injured.
The NYPD received tips after announcing a $12,000 reward in the killing.