The Federal Aviation Administration says local airspace will be restricted from 3 p.m. Saturday to 3:30 a.m. Sunday.
Clinton, the daughter of former President Bill Clinton and Secretary of State Hillary Rodham Clinton, will wed investment banker Marc Mezvinsky on Saturday evening in Rhinebeck. That's about 90 miles north of New York City.
FAA spokesman Jim Peters says Thursday that decisions to restrict air space are made in consultation with other federal agencies. He could not confirm whether the Secret Service requested this one.
The FAA website says the restriction will be in place for "VIP (Very Important Person) Movement" but did not elaborate.
The wedding will take place at a mansion called Astor Courts, where tents have been set up.
Access from the ground is already off limits. Area hotels, including the historic Beekman Arms Inn, are sold out. While the guest list remains top secret, curious onlookers have already descended on the downtown area, not to mention a swarm of media from around the globe.
Then there are the signs -- those congratulating the soon to be newlyweds, some asking Chelsea to change her mind, and others alerting motorists to traffic changes.
Specific road closures will be announced on Friday, but state police say the goal is to keep the flow of traffic moving.
Some information from the Associated Press